Euthyrox (Levothyroxine)

This analytical-grade product functions as an authoritative generic reference standard for laboratories conducting comparative structural characterization, high-throughput metabolic screening, or mass spectrometry calibration. Consisting of a highly refined matrix of Levothyroxine Sodium (T4), this product provides academic institutes, forensic screening centers, and biochemistry laboratories with a standardized chemical baseline necessary for investigating thyroid hormone signaling pathways and enzymatic assays in vitro. Formulated to a strict purity profile of $\ge$98%, this generic compound is synthesized to minimize background analytical noise and eliminate undocumented impurities during quantitative procedures. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Chemical Identity & Classification

This generic chemical reagent belongs to the iodinated tyrosine derivative classification, characterized structurally by a synthetic crystalline tetraiodothyronine core. It is formally categorized as an analytical reference material under the following precise identifiers:

• Formal IUPAC Name: sodium;2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate

• CAS Number: 55-03-8 (anhydrous sodium salt) / 25416-65-3 (hydrate format)

• Molecular Formula: C15​H10​I4​NNaO4​

• Molecular Weight: 798.85 g/mol

• Synonyms: Levothyroxine Sodium, L-Thyroxine Sodium, T4 Sodium Salt, Synthetic O-4-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine

• Classification: Iodinated Tyrosine Derivative, Exogenous Hormone Reference Standard, Analytical Reference Material

Chemical & Physical Characteristics

In its pure form, generic Levothyroxine Sodium presents as a fine, uniform crystalline powder varying from white to off-white or slightly brownish-yellow in appearance. Its unique chemical architecture incorporates a highly lipophilic diphenyl ether core substituted with four iodine atoms and an alanine side-chain side group. This specific halogenated composition dictates its solubility profile; the compound exhibits negligible solubility in pure water or neutral aqueous buffers, but demonstrates excellent solubility in basic alcoholic matrices, dimethyl sulfoxide (DMSO), and alkaline aqueous solutions. The solid-state matrix displays a stable thermodynamic profile under managed laboratory conditions, showing strong resistance to premature thermal decomposition when meticulously shielded from ultraviolet light and ambient humidity.

Purity & Analytical Verification

Every production batch of this generic iodinated amino acid derivative is subjected to mandatory quality control testing to confirm it meets or exceeds a baseline chemical purity of $\ge$98%. Structural identity and quantitative purity margins are verified through advanced laboratory modalities, primarily High-Performance Liquid Chromatography (HPLC) coupled with Ultraviolet detection (HPLC-UV) and Liquid Chromatography-Mass Spectrometry (LC-MS). Absolute molecular configuration, bond arrangements, and iodination positions are validated using Nuclear Magnetic Resonance (NMR) spectroscopy. Batch-specific Certificates of Analysis (COA) are systematically archived, ensuring total data transparency and reliable documentation for compliance auditing.

Quality Control & Batch Integrity

To ensure data reproducibility in multi-phase laboratory investigations, this compound is manufactured under strict lot-controlled conditions. Each distributed unit is stamped with a dedicated batch allocation number, establishing full traceability from raw precursor chemicals to the final refined powder. Strict operational protocols prevent cross-contamination between product runs, ensuring that the crystalline composition remains uniform and free of heavy metals or residual synthesis solvents. This level of batch integrity satisfies the stringent validation demands of academic institutions, independent testing facilities, and international compliance reviews.

Safety, Handling & Laboratory Precautions

As an active, highly potent iodinated tyrosine derivative reagent, this chemical must be handled with appropriate care and only managed by trained laboratory technicians. Standard chemical laboratory safety regulations must be strictly enforced. Personnel are required to wear complete personal protective equipment (PPE), including chemical-resistant nitrile gloves, certified dust-filtering masks, splash-proof safety goggles, and a protective laboratory coat. All sample preparation and mass measurements should be performed within a functioning fume hood or containment enclosure to minimize static airborne dust inhalation or direct dermal contact. This document serves as a high-level overview and does not replace a comprehensive Material Safety Data Sheet (MSDS/SDS).

Packaging, Labeling & Storage

The compound is packaged in professional, research-grade containers, such as light-resistant amber glass vials or heavy-duty foil pouches equipped with a tamper-resistant, moisture-impermeable seal. This protective barrier shields the sensitive ether bonds and iodine atoms from light-catalyzed cleavage or atmospheric hydration. The outer label complies with international chemical commerce and shipping standards, clearly displaying the product name, CAS number, lot code, verified purity, and mandatory handling restrictions. To ensure maximum chemical longevity, store the container tightly closed in a cool, dry, and dark repository maintained strictly between 2°C and 8°C.

Intended Research Use & Market Positioning

This product is positioned strictly within the global chemical supply chain as an in vitro reference standard and analytical reagent. Its primary target markets include endocrine R&D facilities, forensic screening laboratories, university chemistry departments, and industrial research institutions conducting comparative structural activity relationship (SAR) studies. Due to its refined generic formulation, it is optimized for high-performance liquid chromatography injection, calibration curves, and standard qualitative assays. It is entirely unauthorized and unsuited for any clinical trial, veterinary experiment, or live animal modeling.

Ordering, Availability & Fulfillment

We maintain consistent inventory configurations of this generic thyroid reagent to ensure an uninterrupted material pipeline for commercial and academic laboratories. All transactions are securely handled through a WooCommerce infrastructure optimized to satisfy the compliance mandates of primary payment gateways and international customs frameworks. To maintain transport safety and institutional privacy, orders are packed in robust, unbranded, and completely neutral transit materials. Shipments are dispatched with full tracked delivery options, allowing real-time monitoring from our secure facility to your laboratory destination.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. This product is a generic compound sold exclusively for in vitro laboratory experimentation and scientific validation. The purchasing entity assumes full and exclusive responsibility for verifying the specific legal status and scheduling of CAS 55-03-8 within their regional, national, or local jurisdiction before initiating a transaction. The vendor disclaims any and all liability for regulatory infractions, legal consequences, or adverse events resulting from unauthorized handling or use.